Microarray analysis reveals distinctive signaling between the bed nucleus of the stria terminalis, nucleus accumbens, and dorsal striatum
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منابع مشابه
Microarray analysis reveals distinctive signaling between the bed nucleus of the stria terminalis, nucleus accumbens, and dorsal striatum.
To identify distinct transcriptional patterns between the major subcortical dopamine targets commonly studied in addiction we studied differences in gene expression between the bed nucleus of the stria terminalis (BNST), nucleus accumbens (NAc), and dorsal striatum (dStr) using microarray analysis. We first tested for differences in expression of genes encoding transcripts for common neurotrans...
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The activity of neurons in the anterolateral cell group of the bed nucleus of the stria terminalis (BNST(ALG)) plays a critical role in anxiety- and stress-related behaviors. Histochemical studies have suggested that multiple distinct neuronal phenotypes exist in the BNST(ALG). Consistent with this observation, the physiological properties of BNST(ALG) neurons are also heterogeneous, and three ...
متن کاملاثرات داروهای هیستامینرژیک در bed nucleus of the stria terminalis (bnst) رت ها در تست elevated plus maze بر رفتارهای شبه اضطرابی
سیستم هیستامینرژیک مرکزی دارای تاثیرات تنظیمی بر رفتارهای شبه اضطرابی هم در حیوانات و هم در انسان است. این تاثیرات از طریق رسپتور h1 و h2 میانجیگری میشود. تست epm(elevatd plus-maze( برای بررسی تاثیرات اضطراب زایی یا اضطراب زدایی داروها در جوندگان بکار میرود. شواهد نشان می دهند که فعالیت (bnst) bed nucleus the stria terminalis رفتار شبه اضطرابی را در انسانها و حیوانات تنظیم می کند. در مطالعه حاض...
15 صفحه اولMechanisms of Neuroplasticity and Ethanol’s Effects on Plasticity in the Striatum and Bed Nucleus of the Stria Terminalis
Long-lasting changes in synaptic function (i.e., synaptic plasticity) have long been thought to contribute to information storage in the nervous system. Although synaptic plasticity mainly has adaptive functions that allow the organism to function in complex environments, it is now clear that certain events or exposure to various substances can produce plasticity that has negative consequences ...
متن کاملDorsal and ventral distribution of excitable and synaptic properties of neurons of the bed nucleus of the stria terminalis.
The bed nucleus of the stria terminalis (BNST) is a structure uniquely positioned to integrate stress information and regulate both stress and reward systems. Consistent with this arrangement, evidence suggests that the BNST, and in particular the noradrenergic input to this structure, is a key component of affective responses to drugs of abuse. We have utilized an in vitro slice preparation fr...
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ژورنال
عنوان ژورنال: Physiological Genomics
سال: 2008
ISSN: 1094-8341,1531-2267
DOI: 10.1152/physiolgenomics.00224.2006